Selina Koch

Early signals stack up: Two small molecules activate GCase in Parkinson’s Gain reports GCase substrate reduction in CNS; Vanqua shows peripheral enzyme activation plus CNS penetration Gain Therapeutics’ new Phase Ib data mark the second report in as many ... See more

ARTICLE | Product Development AC Immune’s Parkinson’s vaccine advances on promising biomarker profile A coherent suite of α-synuclein, NfL, GFAP and DaT-SPECT findings points to the possibility of disease modification December 11, 2025 11:53 PM UTC A cons... See more

ARTICLE | Product Development Kymera readout hints at new era for degraders in immunology Oral STAT6 program shows biologics-like biomarker activity in Phase Ib atopic dermatitis study, sending biotech’s shares up 42% December 9, 2025 1:55 AM UTC Kymera h... See more

Semaglutide was supposed to quench CNS inflammation — it didn’t The GLP-1’s anti-inflammatory effects in the periphery did not translate to the brain If semaglutide’s failure to treat Alzheimer’s disease has a silver lining, it may be that its inability t... See more

Inside precision oncology’s next chapter with Bill Hinshaw Novartis veteran and Fore CEO on diagnostics, fragmentation, and the operational realities behind today’s precision paradigm: The BioCentury Show When Bill Hinshaw looks back across the arc of his... See more